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Name and Principal Position | | | Year | | | Salary ($) | | | Bonus ($)(1) | | | Stock Awards(2) ($) | | | Option Awards(2) ($) | | | All Other Compensation ($) | | | Total ($) | | ||||||||||||||||||
Stephen From, President and Chief Executive Officer | | | 2017 | | | | | 400,000 | | | | | | 200,000 | | | | | | 91,200 | | | | | | 183,750 | | | | | | — | | | | | | 874,950 | | |
| 2016 | | | | | 400,000 | | | | | | 275,000 | | | | | | — | | | | | | 246,863 | | | | | | — | | | | | | 921,863 | | | ||
Barbara Wirostko, Chief Medical Officer | | | 2017 | | | | | 280,000 | | | | | | 68,811 | | | | | | 22,800 | | | | | | 40,600 | | | | | | — | | | | | | 412,211 | | |
| 2016 | | | | | 213,692 | | | | | | — | | | | | | — | | | | | | 90,016 | | | | | | — | | | | | | 303,708 | | | ||
Michael Manzo, Vice President of Engineering | | | 2017 | | | | | 250,000 | | | | | | 75,000 | | | | | | — | | | | | | 55,100 | | | | | | — | | | | | | 380,100 | | |
| 2016 | | | | | 250,000 | | | | | | 105,000 | | | | | | — | | | | | | 55,949 | | | | | | — | | | | | | 410,949 | | |
Name | | | Grant Date | | | Number of Securities Underlying Unexercised Options (#) Vested | | | Number of Securities Underlying Unexercised Options (#) Unvested | | | Option Exercise Price ($) | | | Option Expiration Date | | |||||||||
Stephen From | | | 15-Apr-08 | | | | | 27,803 | | | | | | — | | | | | | 0.65 | | | | 15-Apr-18 | |
| | | 23-Jan-09 | | | | | 2,156 | | | | | | — | | | | | | 0.65 | | | | 23-Jan-19 | |
| | | 23-Jan-09 | | | | | 278 | | | | | | — | | | | | | 0.65 | | | | 23-Jan-19 | |
| | | 29-Jan-10 | | | | | 54,008 | | | | | | — | | | | | | 0.65 | | | | 29-Jan-20 | |
| | | 25-Jun-10 | | | | | 34,672 | | | | | | — | | | | | | 0.65 | | | | 25-Jun-20 | |
| | | 14-Jan-11 | | | | | 4,553 | | | | | | — | | | | | | 0.65 | | | | 14-Jan-21 | |
| | | 14-Jan-11 | | | | | 47,438 | | | | | | — | | | | | | 0.65 | | | | 14-Jan-21 | |
| | | 23-Dec-12 | | | | | 10,928 | | | | | | — | | | | | | 0.65 | | | | 23-Dec-22 | |
| | | 19-Feb-15 | | | | | 3,642 | | | | | | — | | | | | | 6.00 | | | | 19-Feb-25 | |
| | | 24-Feb-15 | | | | | 167,708 | | | | | | 7,292(2) | | | | | | 5.75 | | | | 24-Feb-25 | |
| | | 28-Aug-15 | | | | | 41,666 | | | | | | 8,334(2) | | | | | | 3.59 | | | | 28-Aug-25 | |
| | | 25-Jan-16 | | | | | 12,777 | | | | | | 7,223(1) | | | | | | 1.70 | | | | 25-Jan-26 | |
| | | 29-Mar-16 | | | | | 31,226 | | | | | | 22,305(1) | | | | | | 3.05 | | | | 29-Mar-26 | |
| | | 18-Jul-16 | | | | | 32,655 | | | | | | 36,497(1) | | | | | | 2.42 | | | | 18-Jul-26 | |
| | | 18-May-17 | | | | | 25,000 | | | | | | — | | | | | | 1.80 | | | | 18-May-27 | |
| | | 21-Jun-17 | | | | | — | | | | | | 125,000(1) | | | | | | 1.35 | | | | 21-Jun-27 | |
Barbara Wirostko | | | 7-Mar-16 | | | | | 22,332 | | | | | | 15,954(1) | | | | | | 3.80 | | | | 7-Mar-26 | |
| | | 29-Mar-16 | | | | | 2,001 | | | | | | 1,430(1) | | | | | | 3.05 | | | | 29-Mar-26 | |
| | | 18-Jul-16 | | | | | 2,156 | | | | | | 2,410(1) | | | | | | 2.42 | | | | 18-Jul-26 | |
| | | 21-Jun-17 | | | | | — | | | | | | 35,000(1) | | | | | | 1.35 | | | | 21-Jun-27 | |
Michael Manzo | | | 15-Apr-08 | | | | | 3,436 | | | | | | — | | | | | | 0.65 | | | | 15-Apr-18 | |
| | | 23-Jan-09 | | | | | 268 | | | | | | — | | | | | | 0.65 | | | | 23-Jan-19 | |
| | | 23-Jan-09 | | | | | 1,366 | | | | | | — | | | | | | 0.65 | | | | 23-Jan-19 | |
| | | 29-Jan-10 | | | | | 6,885 | | | | | | — | | | | | | 0.65 | | | | 29-Jan-20 | |
| | | 25-Jun-10 | | | | | 4,567 | | | | | | — | | | | | | 0.65 | | | | 25-Jun-20 | |
| | | 14-Jan-11 | | | | | 1,366 | | | | | | — | | | | | | 0.65 | | | | 14-Jan-21 | |
| | | 14-Jan-11 | | | | | 6,400 | | | | | | — | | | | | | 0.65 | | | | 14-Jan-21 | |
| | | 23-Dec-12 | | | | | 10,928 | | | | | | — | | | | | | 0.65 | | | | 23-Dec-22 | |
| | | 19-Feb-15 | | | | | 3,187 | | | | | | — | | | | | | 6.00 | | | | 19-Feb-25 | |
| | | 24-Feb-15 | | | | | 47,916 | | | | | | 2,084(2) | | | | | | 5.75 | | | | 24-Feb-25 | |
| | | 28-Aug-15 | | | | | 8,333 | | | | | | 1,667(2) | | | | | | 3.59 | | | | 28-Aug-25 | |
| | | 25-Jan-16 | | | | | 3,194 | | | | | | 1,806(1) | | | | | | 1.70 | | | | 25-Jan-26 | |
| | | 29-Mar-16 | | | | | 7,005 | | | | | | 5,004(1) | | | | | | 3.05 | | | | 29-Mar-26 | |
| | | 18-Jul-16 | | | | | 7,352 | | | | | | 8,217(1) | | | | | | 2.42 | | | | 18-Jul-26 | |
| | | 06-Feb-17 | | | | | — | | | | | | 15,000(1) | | | | | | 1.52 | | | | 06-Feb-27 | |
| | | 18-May-17 | | | | | 8,000 | | | | | | — | | | | | | 1.80 | | | | 18-May-27 | |
| | | 21-Jun-17 | | | | | — | | | | | | 20,000(1) | | | | | | 1.35 | | | | 21-Jun-27 | |
Name(1) | | | Fees earned or paid in cash ($) | | | Option awards ($)(2)(3) | | | Total ($) | | |||||||||
Paul Chaney | | | | $ | 72,500 | | | | | | 17,400 | | | | | $ | 89,900 | | |
Morton Goldberg | | | | $ | 38,500 | | | | | | 17,400 | | | | | $ | 55,900 | | |
Praveen Tyle | | | | $ | 59,750 | | | | | | 17,400 | | | | | $ | 77,150 | | |
Thomas Balland | | | | $ | 35,000 | | | | | | 17,400 | | | | | $ | 52,400 | | |
Thomas E. Hancock | | | | $ | 55,000 | | | | | | 17,400 | | | | | $ | 72,400 | | |
Bernard Malfroy-Camine | | | | $ | 47,000 | | | | | | 17,400 | | | | | $ | 64,400 | | |
| | | Common Stock Beneficially Owned | | |||||||||
Name of Beneficial Owner(1) | | | Shares | | | Percent(2) | | ||||||
5% or Greater Stockholders | | | | | | | | | | | | | |
Entities affiliated with Ventech SA(3) 47, avenue de l’Opéra Paris, France 75002 | | | | | 2,773,718 | | | | | | 6.6% | | |
Armistice Capital Master Fund, Ltd.(4) 510 Madison Avenue, 22nd Floor New York, NY 10022 | | | | | 16,742,500 | | | | | | 40.0% | | |
Executive Officers and Directors | | | | | | | | | | | | | |
Stephen From(5) | | | | | 1,178,803 | | | | | | 2.8% | | |
Barbara Wirostko(6) | | | | | 339,227 | | | | | | * | | |
Michael Manzo(7) | | | | | 163,933 | | | | | | * | | |
Paul Chaney(8) | | | | | 167,388 | | | | | | * | | |
Morton Goldberg(9) | | | | | 62,531 | | | | | | * | | |
Praveen Tyle(10) | | | | | 98,944 | | | | | | * | | |
Thomas Balland(11) | | | | | 44,525 | | | | | | * | | |
Thomas E. Hancock(12) | | | | | 47,819 | | | | | | * | | |
Bernard Malfroy-Camine(13) | | | | | 62,696 | | | | | | * | | |
Steven J. Boyd(4) | | | | | 16,742,500 | | | | | | 40% | | |
Peter Greenleaf (nominee) | | | | | — | | | | | | * | | |
All current executive officers, directors and nominees as a group (total 11 persons)(14) | | | | | 18,908,366 | | | | | | 43.9% | | |
Plan Category | | | Number of Securities to be Issued Upon Exercise of Outstanding Options, Restricted Stock Units, Warrants and Rights | | | Weighted Average Exercise Price of Outstanding Options, Warrants, and Rights | | | Number of Securities Remaining Available For Future Issuance Under Equity Compensation Plans (Excluding Securities Reflected in Column (a)) | | |||||||||
| | | (a) | | | (b) | | | (c) | | |||||||||
Equity compensation plans approved by security holders(1) | | | | | 2,488,714 | | | | | $ | 2.49 | | | | | | 116,411 | | |
Equity compensation plans not approved by security holders | | | | | — | | | | | | — | | | | | | — | | |
Total | | | | | 2,488,714 | | | | | $ | 2.49 | | | | | | 116,411 | | |
| | | 2016 | | | 2017 | | ||||||
Audit Fees(1) | | | | $ | 171,621 | | | | | $ | 272,200 | | |
Audit-Related Fees(2) | | | | $ | 18,000 | | | | | $ | — | | |
Tax Fees(3) | | | | $ | — | | | | | $ | — | | |
All Other Fees(4) | | | | $ | — | | | | | $ | — | | |
Total Fees | | | | $ | 189,621 | | | | | $ | 272,200 | | |
| | | Common Stock Beneficially Owned | | |||||||||
Name of Beneficial Owner | | | Shares | | | Percent | | ||||||
5% or Greater Stockholders | | | | | | | | | | | | | |
Armistice Capital Master Fund, Ltd.(3) | | | | | 2,131,101 | | | | | | 5.5% | | |
510 Madison Avenue, 22nd Floor New York, NY 10022 | | | | | | | | | | | | | |
Named Executive Officers and Directors | | | | | | | | | | | | | |
Brian M. Strem, Ph.D.(4) | | | | | 66,237 | | | | | | * | | |
Eric Daniels, MD, MBA(5) | | | | | 9,520 | | | | | | * | | |
Paul Chaney(6) | | | | | 20,323 | | | | | | * | | |
Kenneth Gayron(7) | | | | | 1,889 | | | | | | * | | |
David Hollander, MD, MBA | | | | | — | | | | | | * | | |
Erin Parsons | | | | | — | | | | | | * | | |
Aron Shapiro(8) | | | | | 1,889 | | | | | | * | | |
Praveen Tyle(9) | | | | | 18,010 | | | | | | * | | |
All current executive officers and directors as a group (total 8 persons)(10) | | | | | 117,868 | | | | | | * | | |
| | | 2020 | | | 2021 | | ||||||
Audit Fees(1) | | | | $ | 171,600 | | | | | $ | 226,430 | | |
Audit-Related Fees(2) | | | | $ | 25,153 | | | | | $ | — | | |
Tax Fees(3) | | | | $ | — | | | | | $ | — | | |
All Other Fees(4) | | | | $ | — | | | | | $ | — | | |
Total Fees | | | | $ | 196,753 | | | | | $ | 226,430 | | |